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Clinical Trial Search Results

Baystate has clinical trials in several medical specialties. Clinical trials can help our patients by making advanced care available to them right in their communities.

Is volunteering for a clinical trial right for you? Learn more.

Page 1 of 7 | Results 1 - 10 of 63

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients with Multivessel Coronary Artery Disease: Fractional Flow Reserve versus Angiography for Multivessel Evaluation (FAME) 3 Trial

The purpose of this study is to demonstrate that Fractional Flow Reserve (FFR)-guided Percutaneous Coronary Intervention (PCI) is non-inferior to coronary artery bypass graft surgery (CABG) in patients with multi-vessel Coronary Artery Disease (CAD). FFF-guided PCI might result in lower rates of death, heart attack, and the need for repeat revascularization as compared to what was seen after CABG surgery. There is also the possibility of a chance at a shorter recovery time with the minimally invasive FFR-guided PCI versus CABG surgery.
Dr. Amir Lotfi
Heart

Baystate Medical Center 759 Chestnut Street Springfield, MA 01199

A Metastatic breast cancer trial

Grace Makari-Judson, MD
Cancer - Breast, Cancer

D'Amour Center for Cancer Care
3350 Main Street
Springfield, MA 01199

A Phase 1b/2a, Randomized, Double-Blinded, Placebo-Controlled, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-936559 in Subjects with Severe Sepsis

The purpose of this study is to evaluate the safety and potential efficacy signal of the study drug, BMS-936559, in subjects with severe sepsis.

Tidswell, Mark, MD
Infection

Baystate Medical Center 759 Chestnut Street Springfield, MA 01199

A Phase II trial to study Stage IV Squamous Cell Lung Cancer (Lung-MAP study)

John McCann, MD
Cancer, Cancer - Lung

D'Amour Center for Cancer Care
3350 Main Street
Springfield, MA 01199

A Phase III trial evalutaing use of adjuvant endorcrine therapy in patients with high-risk hormone receptor-positive and HER2/negative Breast Cancer

The purpose of this study is to see whether treatment with everolimus plus hormone treatment after chemotherapy will increase the time without your cancer returning.  The current standard treatment after chemotherapy is hormone treatment alone. The combination of hormone-treatment and everolimus is experimental in patients with breast cancer.
Grace Makari-Judson, MD
Cancer - Breast, Cancer

D’Amour Center for Cancer Care
3350 Main Street
Springfield, MA 01199

A Phase III trial to assess efficacy and safety of chemotherapy as an adjuvant treatment for patients with BRCA1/2 Mutations and high risk Her2 negative primary breast cancer

Grace Makari-Judson, MD
Cancer, Cancer - Breast

D’Amour Center for Cancer Care
3350 Main Street
Springfield MA 01199

A Phase III trial to study post-operative radiation therapy for endometrial and cervical cancer

The purpose of this study is to test whether the use of a radiation therapy delivery technique called intensity-modulated radiation therapy (IMRT) can reduce the amount and severity of gastrointestinal side effects (such as diarrhea) that result from radiation, compared with standard radiation techniques
Seth Kaufman, MD
Cancer-Gynecologic, Cancer

D’Amour Center for Cancer Care
3350 Main Street
Springfield MA 01199

A Prospective, Randomized, Controlled Study to Evaluate the Effectiveness and Safety of CELSTAT as an Adjunct to Hemostasis for Tissue Bleeding in Cardiothoracic, General and Vascular Surgery

The purpose of this study is to compare the effectiveness and safety of CELSTAT versus Sergicel for treating tissue bleeding in patients undergoing cardiothoracic, general and vascular surgery.
John Rousou, MD
Surgery

Baystate Medical Center

759 Chestnut Street

Springfield, MA 01199

A Randomised Controlled Study to Evaluate the Efficacy and Safety of Fibrin Sealant, Vapour Heated, Solvent/Detergent Treated (FS VH S/D 500 s apr) Compared to DuraSeal Dural Sealant as an Adjunct to Sutured Dural Repair in Cranial Surgery

The purpose of this study is to evaluate the safety and efficacy of the study drug, FS VH S/D 500 s-apr, compared to DuraSeal Dural Sealant as an additional aid to sutured dural (membrane that covers and protects the brain and spinal cord) closure.
Dr. Dennis Oh
Surgery

Baystate Medical Center 759 Chestnut Street Springfield, MA 01199

A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chest Wall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy

This study evaluates whether the addition of chestwall + regional nodal XRT after mastectomy or breast + regional nodal XRT after breast conserving surgery will significantly reduce the rate of events for invasive breast cancer recurrence-free interval (IBC-RFI) in patients who present with histologically positive axillary nodes but convert to histologically negative axillary nodes following neoadjuvant chemotherapy.

Seth Kaufman, MD
Cancer - Breast

D'Amour Center for Cancer Care 

Page 1 of 7 | Results 1 - 10 of 63