A Home-Based Study to Enhance Activity in Breast Cancer Survivors

October 01, 2016
776553
Cancer, Cancer - Breast
Grace Makari-Judson, MD
D’Amour Center for Cancer Care, 3350 Main Street, Springfield, MA

There is a well-documented association between physical activity & risk for breast cancer development and recurrence. It is known that exercise interventions have been effective at increasing physical activity levels in breast cancer survivors. Knowing that breast cancer survivors are less active than non-cancer patients, a less active lifestyle places them at risk of obesity and poor overall health, which in turn also increases risk of cancer and cancer recurrence. Not all the reasons for the risk reduction are clear, however it is known that hormones and other inflammatory markers play a role.

This study has three goals:
1. To investigate the feasibility of a home intervention designed to reduce sedentary behavior.
2. Describe the effects of the intervention on levels of sedentary behavior, physical activity, and symptoms.
3. Assess cost of the intervention.

Inclusion Criteria:

• Stage I-III breast cancer survivors 20-80 who have completed primary treatment (surgery, radiation and/or chemotherapy) greater than 6 months but less than 5 years ago. Patients may be on adjuvant hormonal therapy
• BMI > 25 (overweight or class I/II obese)
• Not meeting current guidelines for regular exercise as defined by less than 150 minutes a week of moderate to vigorous physical activity
• No gain or loss of >10% body weight over the prior 6 months.

Exclusion Criteria:

• Known diabetes
• Known coronary artery disease
• Pregnancy
• Any injury that would limit mobility or require use of assisted mobility devices
• Weight gain or loss of >10% body weight over the prior 6 months
• Greater than 150 minutes a week of moderate to vigorous physical activity
• Inability to provide informed consent
• Non-english speaking

Active
Interventional (Clinical Trial), Single Group Assignment
Ruth Barham
413-794-3186