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Heart Disease Trials

Click on a trial to find out the eligibility requirements and who to contact if you have questions about participating.

Page 1 of 1 | Results 1 - 6 of 6

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients with Multivessel Coronary Artery Disease: Fractional Flow Reserve versus Angiography for Multivessel Evaluation (FAME) 3 Trial

The purpose of this study is to demonstrate that Fractional Flow Reserve (FFR)-guided Percutaneous Coronary Intervention (PCI) is non-inferior to coronary artery bypass graft surgery (CABG) in patients with multi-vessel Coronary Artery Disease (CAD). FFF-guided PCI might result in lower rates of death, heart attack, and the need for repeat revascularization as compared to what was seen after CABG surgery. There is also the possibility of a chance at a shorter recovery time with the minimally invasive FFR-guided PCI versus CABG surgery.
Dr. Amir Lotfi
Heart

Baystate Medical Center 759 Chestnut Street Springfield, MA 01199

Door To Unloading With IMPELLA CP System in Acute Myocardial Infarction to Reduce Infarct Size (DTU): A Prospective Feasibility Study

Evan Lau, MD
Heart

Davis Family Heart & Vascular Center

Baystate Medical Center

759 Chestnut Street

Springfield, MA 01199

Physiologic Assessment of Coronary Stenosis Following PCI (DEFINE PCI)

Amir Lotfi, MD
Heart

Davis Family Heart & Vascular Center

Baystate Medical Center

759 Chestnut Street Springfield, MA 01199

Prospective, Multicenter, Single Arm Safety and Effectiveness Study of Endovascular Abdominal Aortic Aneurysm Repair using the Nellix® System

The objective of this study is to assess the safety and effectiveness of the Endologix® EndoVascular Aneurysm Sealing System for the repair of abdominal aortic aneurysms (AAA).
Neal Hadro, MD
Heart

Baystate Medical Center
759 Chestnut St.
Springfield, MA 01199

REPRIEVE (A5332) - Randomized Trial to Prevent Vascular Events in HIV

The purpose of this study is to test the efficacy of 4 mg Pitavastatin daily on cardiovascular-related events among HIV-1 infected adults.

Daniel J. Skiest, MD
HIV, Heart

Baystate Infectious Diseases Clinical Research

3300 Main Street

Springfield, MA 01199

Transcatheter Aortic Valve Replacement With the Medtronic Transcatheter Aortic Valve Replacement System In Patients at Low Risk for Surgical Aortic Valve Replacement

The purpose of this study is to demonstrate that the safety and effectiveness of the Medtronic Transcatheter Aortic Valve Replacement (TAVR) system as measured by rates of all-cause mortality or disabling stroke at two years is non-inferior to Surgical Aortic Valve Replacement (SAVR) in the treatment of severe aortic stenosis in subjects who have a low predicted risk of operative mortality for SAVR.

Dr. Ashequl Islam
Heart

Baystate Medical Center 759 Chestnut Street, Springfield, MA 01199

Page 1 of 1 | Results 1 - 6 of 6