Preimplantation Genetic Testing
We offer preimplantation genetic testing (diagnosis and screening) for those undergoing in vitro fertilization (IVF). Our experienced reproductive physicians, nurses, and embryologists work together to help you achieve a healthy pregnancy.
The following diagnostic and screening tests must be done in conjunction with an in vitro fertilization cycle. Results are usually available within 7-12 days.
Preimplantation Genetic Diagnosis
Preimplantation genetic diagnosis (PGD) is a procedure used to diagnose genetic disease in an embryo, including gene disorders and chromosomal translocation.We work with a specialized genetics lab to provide personalized testing, unique to you (and/or your partner) and your chromosome(s).
Gene disorders are caused when either one or both partners carry a gene that can cause a life threatening or chronic disease. Some common examples of such diseases include:
- Sickle Cell Anemia
- Duchenne's Muscular Dystrophy
- Cystic Fibrosis
A chromosomal translocation occurs when a parent has the correct amount of chromosomal material, but that material is not where it should be. The chromosomal translocation does not cause any problems in the parent, but can cause miscarriage.
PGD allows us to identify disease free embryos which can then be used to try to initiate a healthy pregnancy.
Preimplantation Genetic Screening
We also screen embryos for aneuploidy, a condition in which an embryo has an extra or missing chromosome. Aneuploidy is associated with conditions such as Down's syndrome.
In preimplantation genetic screening (PGS), each embryo is screened for the correct number of chromosomes. PGS reduces the miscarriage rate, and is recommended for people who have had repeated pregnancy losses. You might also choose PGS if you have had repeated IVF failures or are of advanced maternal age.