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Patients and Visitors Learn About Clinical Trials Find a Clinical Trial Pulmonary and Critical Care Medicine

Pulmonary and Critical Care Medicine

Page 1 of 7 | Results 1 - 10 of 62

D14122 Phase II study of Pre-emptive OsciLLation of ER activitY levels through alternation of estradiol/anti-estrogen therapies prior to disease progression in ER+/HER2- metastatic breast cancer (POLLY)

Grace Makari-Judson, MD
Cancer - Breast, Cancer

D'Amour Center for Cancer Care

3350 Main Street
Springfield, MA 01199

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients with Multivessel Coronary Artery Disease: Fractional Flow Reserve versus Angiography for Multivessel Evaluation (FAME) 3 Trial

The purpose of this study is to demonstrate that Fractional Flow Reserve (FFR)-guided Percutaneous Coronary Intervention (PCI) is non-inferior to coronary artery bypass graft surgery (CABG) in patients with multi-vessel Coronary Artery Disease (CAD). FFF-guided PCI might result in lower rates of death, heart attack, and the need for repeat revascularization as compared to what was seen after CABG surgery. There is also the possibility of a chance at a shorter recovery time with the minimally invasive FFR-guided PCI versus CABG surgery.
Dr. Amir Lotfi
Heart

Baystate Medical Center 759 Chestnut Street Springfield, MA 01199

A Home Based Study to Enhance Activity in Breast Cancer Survivors

Grace Makari-Judson, MD
Cancer, Cancer - Breast

D'Amour Center for Cancer Care

3350 Main Street
Springfield, MA 01199

A PHASE III, MULTICENTER, RANDOMIZED, STUDY OF ATEZOLIZUMAB VERSUS PLACEBO ADMINISTERED IN COMBINATION WITH PACLITAXEL, CARBOPLATIN, AND BEVACIZUMAB TO PATIENTS WITH NEWLY-DIAGNOSED STAGE III OR STAGE IV OVARIAN, FALLOPIAN TUBE, OR PRIMARY PERITONEAL CANCER (GOG 3015)

Tashanna Myers, MD
Cancer-Gynecologic, Cancer

D'Amour Center for Cancer Care

3350 Main Street
Springfield, MA 01199

A Phase 1b/2a, Randomized, Double-Blinded, Placebo-Controlled, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-936559 in Subjects with Severe Sepsis

The purpose of this study is to evaluate the safety and potential efficacy signal of the study drug, BMS-936559, in subjects with severe sepsis.

Tidswell, Mark, MD
Infection

Baystate Medical Center 759 Chestnut Street Springfield, MA 01199

A Phase II Study of Talazoparib (BMN 673) in Patients with Homologous Recombination Repair Deficiency Positive Stage IV Squamous Cell Lung Cancer (Lung-MAP Sub-Study)

John McCann, MD
Cancer, Cancer - Lung

D'Amour Center for Cancer Care

3350 Main Street
Springfield, MA 01199

A Phase II Trial Evaluating Cisplatin (NSC #119875) And Gemcitabine (NSC # 613327) Concurrent With Intensity-Modulated Radiation Therapy (IMRT) In The Treatment Of Locally Advanced Squamous Cell Carcinoma Of The Vulva

The purpose of this study is to find out if radiation therapy along with the addition of the drugs, cisplatin and gemcitabine, works and to find out what side effects or surgical complications are caused by treatment with this combination.
Tashanna Myers, MD
Cancer-Gynecologic, Cancer

D’Amour Center for Cancer Care

3350 Main Street, Springfield MA 01199

Franklin Medical Center

164 High Street, Greenfield MA

A Phase III Prospective Randomized Trial Of Dose-Escalated Radiotherapy With Or Without Short-Term Androgen Deprivation Therapy For Patients With Intermediate-Risk Prostate Cancer

The purpose of this study is to compare the effects of dose-escalated radiation therapy with or without hormone therapy on your prostate cancer.
Seth Kaufman, MD
Cancer - Prostate, Cancer

D’Amour Center for Cancer Care

3350 Main Street, Springfield MA 01199

A Phase III Randomized Study of Nivolumab Plus Ipilimumab Versus Nivolumab for Previously Treated Patients with Stage IV Squamous Cell Lung Cancer and No Matching Biomarker

John McCann, MD
Cancer, Cancer - Lung

D'Amour Center for Cancer Care

3350 Main Street
Springfield, MA 01199

A Phase III Trial Evaluating The Addition Of Trastuzumab To Trimodality Treatment Of HER2-Overexpressing Esophageal Adenocarcinoma

Seth Kaufman, MD
Cancer - Esophogus, Cancer

D’Amour Center for Cancer Care

3350 Main Street, Springfield MA 01199

Page 1 of 7 | Results 1 - 10 of 62