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Infectious Disease Trials

Click on a trial to find out the eligibility requirements and who to contact if you have questions about participating.

Page 1 of 1 | Results 1 - 6 of 6

A Double-blind, Randomised, Placebo-controlled, Phase 2b/3 Adaptive Clinical Trial Investigating the Efficacy and Safety of Selepressin as Treatment for Patients with Vasopressor-dependent Septic Shock

Mark Tidswell, MD
Infection

Baystate Medical Center

759 Chestnut Street

Springfield, MA  01199

A Phase 1b/2a, Randomized, Double-Blinded, Placebo-Controlled, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-936559 in Subjects with Severe Sepsis

The purpose of this study is to evaluate the safety and potential efficacy signal of the study drug, BMS-936559, in subjects with severe sepsis.

Tidswell, Mark, MD
Infection

Baystate Medical Center 759 Chestnut Street Springfield, MA 01199

Evaluating the Use of Polymyxin B Hemoperfusion in a Randomized Controlled Trial of Adults Treated for Endotoxemia and Septic Shock

The purpose of this study is to compare the safety and efficacy of the PMX cartridge in subjects with septic shock in comparison to subjects who receive standard medical care alone.

Mark Tidswell, MD
Infection

Baystate Medical Center
Critical Care Unit
759 Chestnut Street
Springfield, MA 01199

GEMINI 1 - A Phase III, randomised, double-blind, multicentre, parallel- group, non-inferiority study evaluating the efficacy, safety, and tolerability of dolutegravir plus lamivudine compared to dolutegravir plus tenofovir/emtricitabine in HIV-1-infected treatment-naïve adults - 204861

The purpose of this study is to compare safety, efficacy, and tolerability of a two drug regimen of dolutegravir (DTG) plus (+) lamivudine (3TC) administered once daily to the DTG plus Tenofovir [TDF]/Emtricitabine [FTC] fixed dose combination [FDC] administered once daily in human immunodeficiency virus (HIV) 1 infected adult subjects that have not previously received antiretroviral therapy. The study is designed to demonstrate the non-inferior antiviral activity of DTG plus 3TC regimen to that of DTG plus TDF/FTC FDC.
Dr. Daniel Skiest
Infection, HIV

Baystate Medical Center 759 Chestnut Street Springfield, MA 01199

INSIGHT Genomics Study

The purpose of this study is to obtain DNA of people who may have the flu in order to better understand the gene response to those that have a high risk of getting the flu.

Infection

Baystate Infectious Diseases Clinical Research

3300 Main St.

Springfield, MA 01104

The MENDS II Study Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients with Acute Respiratory Failure

The purpose of this study is to determine if sedation of mechanically ventilated severely septic patients with dexmedetomidine have improved outcomes compared to patients on propofol.
Patrick Mailloux, DO
Infection

Baystate Medical Center
Critical Care Unit
759 Chestnut St
Springfield, MA 01199 

Page 1 of 1 | Results 1 - 6 of 6