Physiologic Assessment of Coronary Stenosis Following PCI (DEFINE PCI)
Amir Lotfi, MD
Davis Family Heart & Vascular Center
Baystate Medical Center
759 Chestnut Street Springfield, MA 01199
This is a pilot study designed to assess the relationship between iFR pullback and the distribution of coronary atheroma/stenoses as assessed by Quantitative Coronary Angiography (QCA) post angiographically successful PCI
- Subject must be > 18 years old
- Subjects presenting with stable angina, silent ischemia or non-ST-elevation ACS (unstable angina or biomarker positive)
- Subjects are able and willing to comply with scheduled visits and tests and to provide informed consent.
- Pregnant or planning to become pregnant for the duration of the study
- Acute STEMI within the past 7 days
- Cardiogenic shock (sustained (>10 min) systolic blood pressure < 90 mmHg in absence of inotropic support or the presence of an intra-aortic balloon pump).
- Ionotropic or temporary pacing requirement
- Sustained ventricular arrhythmias
- Prior CABG
- Known ejection fraction ≤30%
- Chronic Total Occlusion (CTO)
- Known severe mitral or aortic stenosis.
- Intra-coronary thrombus on baseline angiography
Annette Scarnici, RN