Randomization of Single vs Multiple Arterial Grafts (ROMA)

The primary hypothesis of ROMA is that in patients undergoing primary isolated non-emergent coronary artery bypass surgery (CABG), the use of two or more arterial grafts compared to a single arterial graft is associated with a reduction in the composite outcome of death from any cause, any stroke, post discharge myocardial infarction and/or repeat revascularization. The secondary hypothesis is that in patients undergoing primary isolated non-emergent CABG, the use of two or more arterial grafts compared to a single arterial graft is associated with improved survival.

I'M INTERESTED

This research study is led by Dr. Daniel Engelman.

Contact: Annette Scarnici, RN, CCRC, 413-794-9076

Participation details:

Ages Eligible for Study: 18 Years to 70 Years (Adult, Older Adult)
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No

Inclusion Criteria:

• Primary isolated CABG patients with disease of the left main coronary artery and/or of the left anterior descending and the circumflex coronary system with or without disease of the right coronary artery.

Exclusion Criteria:

• Age > 70 years
• Evolving myocardial infarction within 48 hours of surgery
• Previous cardiac surgery
• Inability to use the saphenous vein or to use both radial and right internal thoracic arteries