Physiologic Assessment of Coronary Stenosis Following PCI (Percutaneous coronary intervention)

Amir Lotfi, MD
Davis Family Heart & Vascular Center
Baystate Medical Center
759 Chestnut Street
Springfield, MA 01199
This is a pilot study designed to assess the relationship between iFR pullback and the distribution of coronary atheroma/stenoses as assessed by Quantitative Coronary Angiography (QCA) post angiographically successful PCI

Inclusion Criteria:

  1. Subject must be > 18 years old
  2. Subjects presenting with stable angina, silent ischemia or non-ST-elevation ACS (unstable angina or biomarker positive)
  3. Subjects are able and willing to comply with scheduled visits and tests and to provide informed consent.

Exclusion Criteria:

  1. Pregnant or planning to become pregnant for the duration of the study
  2. Acute STEMI within the past 7 days
  3. Cardiogenic shock (sustained (>10 min) systolic blood pressure < 90 mmHg in absence of inotropic support or the presence of an intra-aortic balloon pump).
  4. Ionotropic or temporary pacing requirement
  5. Sustained ventricular arrhythmias
  6. Prior CABG
  7. Known ejection fraction ≤30%
  8. Chronic Total Occlusion (CTO)
  9. Known severe mitral or aortic stenosis.
  10. Intra-coronary thrombus on baseline angiography
Annette Scarnici, RN