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Melanoma/Skin Cancer Trials

Click on a trial to find out the eligibility requirements and who to contact if you have questions about participating.

Page 1 of 1 | Results 1 - 6 of 6

DREAMseq (Doublet, Randomized Evaluation in Advanced Melanoma Sequencing) a Phase III Trial

The purpose of this research study is to compare any good and bad effects of giving ipilimumab, nivolumab, and GM-CSF (Sargramostim) at the same time compared to just ipilimumab and nivolumab together. We would also like to find out what effects, good and bad, that this combination of drugs may have on your cancer.
John McCann, MD
Cancer - Melanoma, Cancer

D’Amour Center for Cancer Care, 3350 Main Street, Springfield, MA

Recruiting

Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

This randomized phase II trial studies how well ipilimumab with or without bevacizumab works in treating patients with stage III-IV melanoma that cannot be removed by surgery. Immunotherapy with monoclonal antibodies, such as ipilimumab and bevacizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
John McCann, MD
Cancer, Cancer - Melanoma

  • D’Amour Center for Cancer Care, 3350 Main Street, Springfield, MA
  • Baystate Franklin Medical Center, 164 High Street, Greenfield, MA

Active

Molecular Analysis for Therapy Choice (MATCH)

John McCann, MD
Cancer, Cancer - Brain, Cancer - Breast, Cancer - Colon, Cancer - Esophogus, Cancer-Gynecologic, Cancer - Kidney, Cancer - Leukemia, Cancer - Lung, Cancer - Lymphoma, Cancer - Melanoma, Cancer - Multiple Myeloma, Cancer - Pancreatic, Cancer - Prostate

D’Amour Center for Cancer Care, 3350 Main Street, Springfield, MA

Recruiting

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors (DART)

John McCann, MD
Cancer, Cancer - Brain, Cancer - Breast, Cancer - Colon, Cancer - Esophogus, Cancer-Gynecologic, Cancer - Kidney, Cancer - Leukemia, Cancer - Lung, Cancer - Lymphoma, Cancer - Melanoma, Cancer - Multiple Myeloma, Cancer - Pancreatic, Cancer - Prostate

  • D’Amour Center for Cancer Care, 3350 Main Street, Springfield, MA
  • Baystate Franklin Medical Center, 164 High Street, Greenfield, MA   

Recruiting

Phase III Randomized Trial Comparing High Dose Interferon to MK-3475 (Pembrolizumab) in Patients with High Risk Resected Melanoma

The purpose of this study is to compare the effects, good and/or bad, of the experimental drug MK-3475 (also called pembrolizumab) to the usual treatment of either interferon alfa-2b or ipilimumab.  In this study, you will get either MK-3475 or a choice of either interferon alfa-2b or ipilimumab. 

John McCann, MD
Cancer - Melanoma

D’Amour Center for Cancer Care, 3350 Main Street, Springfield, MA

Active

Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery

John McCann, MD
Cancer, Cancer - Melanoma

D’Amour Center for Cancer Care, 3350 Main Street, Springfield, MA

Active
Page 1 of 1 | Results 1 - 6 of 6