Selenium in Preventing Tumor Growth in Patients With Previously Resected Stage I Non-small Cell Lung Cancer

Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. It is not yet known if selenium is effective in preventing the growth of new tumors in patients with previously resected non-small cell lung cancer. This randomized phase III trial is studying selenium to see how well it works compared to a placebo in preventing the development of second primary lung tumors in patients who have undergone surgery to remove stage I non-small cell lung cancer.


This research study is led by Dr. John McCann.

Contact: Katie Colbeck, 413-794-9875

Participation details:

October 01, 2000
Cancer - Lung, Cancer
D’Amour Center for Cancer Care, 3350 Main Street, Springfield, MA

Ages Eligible for Study: 18 Years and older (Adult, Older Adult)
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No

Inclusion Criteria:

  • Histologically confirmed, completely resected stage IA (pT1, N0) or IB (pT2, N0) non-small lung cancer (except carcinoid)
  • 18 years old and over
  • Prior mineral, herbal, phytochemical, or vitamin supplementation allowed

Exclusion Criteria:

  • Evidence of new or recurrent lung cancer on chest x-ray within the past 8 weeks
  • History of more than one primary lung cancer at any time
  • Concurrent or other prior cancer within the past 5 years except localized non-melanoma skin cancer
Interventional (Clinical Trial), Randomized