Radiation Therapy, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Locally Advanced Squamous Cell Cancer of the Vulva

The purpose of this study is to find out if radiation therapy along with the addition of the drugs, cisplatin and gemcitabine, works and to find out what side effects or surgical complications are caused by treatment with this combination.

I'M INTERESTED

This research study is led by Dr. Tashanna Myers.

Contact: Laura Sorci, 413-794-3188

Participation Details:

July 02, 2012
369251
Cancer-Gynecologic, Cancer
  • D’Amour Center for Cancer Care, 3350 Main Street, Springfield, MA
  • Baystate Franklin Medical Center, 164 High Street, Greenfield, MA

Inclusion Criteria:

  • Patients with locally advanced, previously untreated squamous cell carcinoma of the vulva
  • Patients with T2 or T3 primary tumors (N0-3, M0) not amenable to surgical resection by standard radical vulvectomy
  • Patients judged capable of tolerating a radical course of chemoradiation therapy
  • Patients must have signed an approved informed consent and authorization permitting release of personal health information

Exclusion Criteria:

  • Patients who have received prior pelvic radiation or cytotoxic chemotherapy
  • Patients with vulvar melanomas or sarcomas
  • Patients with evidence of active septicemia, severe infection, gastrointestinal bleeding or severe gastrointestinal symptoms requiring medical or surgical therapy
Recruiting
2