A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy

Cancer - Breast, Cancer
Seth Kaufmann, MD

D'Amour Center for Cancer Care

3350 Main Street
Springfield, MA 01199

The purpose of this study is to research women who have cancer cells in the lymph nodes at the time that the breast cancer is diagnosed and have chemotherapy before surgery that clears the cancer cells from the lymph nodes.  If, after lumpectomy, radiation to the breast and lymph nodes will be better than radiation only to the breast, and if, after mastectomy, radiation to the area where the breast used to be and to the lymph nodes is better than no radiation.
Lymph node positive breast cancer at time of diagnosis, Neoadjuvant chemotherapy resulting in lymph node negative cancer.
Rae Lynn Defeo